Danek is a nosferatu who has reclaimed his humanity and is now on a mission to destroy his own kind in order to save humankind from the scourge of vampirism. He embarks on a yearslong search for Dr. von Heidenau, a professor who captured him and performed experiments on him and Elizabeth Weston before turning himself into a vampire and eluding them after they escaped. When Danek finally catches up with the professor, von Heidenau is no longer the creature he had been hunting... and Danek forms an uneasy alliance with his erstwhile enemies, Jesuit monks, in order to combat a much greater evil than von Heidenau had ever posed.