This is a brief summary of the current artificial intelligence and machine learning landscape in radiology as we pass 100 FDA 510k cleared algorithms. Following the typical radiology sections, this book reviews products and innovation in neuroradiology, MSK, body, pediatrics, mammography, chest, cardiac, IR and ultrasound. There are additional chapters reviewing workflow and quality platforms as applied to image acquisition and collaboration with clinical colleagues. The pace has quickened to reach this 100-algorithm milestone, making this book ideal for radiologists, residents and medical students who would like a snapshot in time of the past several years of medical imaging innovation.