Major Titus "Wheels" Briggs is fighting the war he vowed to finish. Briggs now commands the elite Joint Strike Force, Crimson Talon against the relentless Thephari. When a catastrophic spreader ship threatens to unleash the deadly Gray Plague virus upon humanity, Briggs must respond forcefully. Orbital Ranger Staff Sergeant First Class Erik Canyon, plunges into the alien jungle to execute a rescue for a missing comrade. The Rangers fight against brutal Scaleys and heavily armored Cobra mechs in an escalating battle that ultimately leads to a grim discovery. Briggs and Canyon know one thing: the Thephari threat must be eradicated in order to bring the long, bloody war to a conclusion.