Antimicrobial Peptides (AMPs) as Next-Generation Antibiotics: A Comprehensive Review " explores the growing significance of AMPs as potential alternatives to conventional antibiotics in combating multidrug-resistant infections. With antibiotic resistance becoming an escalating global threat, this comprehensive review delves into the unique mechanisms, structures, and sources of AMPs, highlighting their broad-spectrum efficacy against bacteria, viruses, fungi, and parasites. The book presents a detailed analysis of AMPs' role in both innate immunity and therapeutic applications, examining their potential to disrupt bacterial membranes, modulate immune responses, and serve as powerful antimicrobial agents. In addition to discussing the latest advances in AMP research, the review provides insights into the challenges and strategies for AMP synthesis, delivery systems, and clinical applications. The future prospects of AMPs as next-generation antibiotics, along with their impact on the pharmaceutical landscape, are also critically evaluated. This comprehensive resource is invaluable for researchers, clinicians, and professionals involved in drug development, biotechnology, and infection control, offering a forward-looking perspective on the potential of AMPs to revolutionize antimicrobial therapies.