“A rigorous, in-depth guide to the history, philosophy, and scientific exploration of this widespread emotional state . . . [LeDoux] offers a magisterial review of the role of mind and brain in the generation of unconscious defense responses and consciously expressed anxiety. . . . [His] charming personal asides give an impression of having a conversation with a world expert.” — Nature A comprehensive and accessible exploration of anxiety, from a leading neuroscientist and the author of Synaptic Self Collectively, anxiety disorders are our most prevalent psychiatric problem, affecting about forty million adults in the United States. In Anxious , Joseph LeDoux, whose NYU lab has been at the forefront of research efforts to understand and treat fear and anxiety, explains the range of these disorders, their origins, and discoveries that can restore sufferers to normalcy. LeDoux’s groundbreaking premise is that we’ve been thinking about fear and anxiety in the wrong way. These are not innate states waiting to be unleashed from the brain, but experiences that we assemble cognitively. Treatment of these problems must address both their conscious manifestations and underlying non-conscious processes. While knowledge about how the brain works will help us discover new drugs, LeDoux argues that the greatest breakthroughs may come from using brain research to help reshape psychotherapy. A major work on one of our most pressing mental health issues, Anxious explains the science behind fear and anxiety disorders. Praise for Anxious : “[ Anxious ] helps to explain and prevent the kinds of debilitating anxieties all of us face in this increasingly stressful world.” —Daniel J. Levitin, author of The Organized Mind and This Is Your Brain on Music “A careful tour through the current neuroscience of fear and anxiety . . . [ Anxious ] will reward the informed reader.” — The Wall Street Journal “An extraordinarily ambitious, provocative, challenging, and important book. Drawing on the latest research in neuroscience (including work in his own laboratory), LeDoux provides explanations of the origins, nature, and impact of fear and anxiety disorders.” — Psychology Today “Every age believes itself to be the age of anxiety, as Auden’s famous poem first put it. But in his new book, Anxious , the neuroscientist and writer Joseph LeDoux suggests that that has never been a stronger claim to make than it is now . . . . If this is the age of anxiety, LeDoux is our Lewis and our Clark: It was LeDoux who laid down the first map of what is called the brain’s ‘fear circuit,’ the regions—centered on the amygdala and its adjacent structures—that together give rise to our ability to respond to threats and danger. But with his new book, he wants to redraw that map.” —Casey Schwartz , New York Magazine “Mr. LeDoux offers a careful tour through the current neuroscience of fear and anxiety. . . . [ Anxious ] will reward the informed reader.” —Leonore Tiefer , The Wall Street Journal “LeDoux presents a rigorous, in-depth guide to the history, philosophy and scientific exploration of this widespread emotional state. . . . Neuroscientists, psychologists, philosophers and psychiatrists will find this exquisitely referenced book particularly useful. It is also a must-read for young investigators, and anyone perusing the footnotes will be rewarded with an insider’s view of the state and evolution of anxiety research. LeDoux’s charming personal asides give an impression of having a conversation with a world expert. LeDoux ends on a high note, describing how cutting-edge research on the neural substrates of anxiety is being translated into new approaches for psychiatric treatment.” —Susanne Ahmari, Nature “LeDoux is not only a pioneer in the neurobiological analysis of fear in animals but also a scholarly and accessible writer. In Anxious , he systematically builds on his earlier works, covering with aplomb a vast literature on emotion, memory, attention, and consciousness. With that said, Anxious is a significant and important departure from the author’s earlier views on the neural underpinnings of fear. . . . In Anxious , LeDoux challenges the reader to think differently about the neural origins of fear and its disorders. In doing so, he offers a masterful synthesis of animal and human work and a novel roadmap for future work in both the laboratory and the clinic.” —Stephen Maren, Science “Anxious is an extraordinarily ambitious, provocative, challenging, and important book. Drawing on the latest research in neuro-science (including work in his own laboratory), LeDoux provides explanations of the origins, nature, and impact of fear and anxiety disorders.” —Glenn Altschuler, Psychology Today “Drawing on years of research, neuroscientist LeDoux delves into the subject of anxiety and fear, depicting both emotions as cognitive constructs. . . . [ Anxious ] will open up new worlds of thin