The Blossoms are six mature ladies with humorous personalities and are lifetime friends. Each year they meet up and have a Mediterranean cruise, only this year on board the ship is a killer, who strikes at night when others are sleeping. The Blossoms – ever excited about watching murder mysteries on the television – decide to put their minds to the test and solve the murder, before the killer can strike again. They sneak, duck and dive around the ship and on land, ever following those they think could be the culprit, not realizing they are putting themselves in danger. Spending the night with a corpse for company does not shudder their resolve, nor thwarting an attempted bank robbery. In a collision of fearful activity, they stumble across the murderer. The killer can’t let them win, and murder is the only way to escape the Blossoms’ trap.