This United States Coast Guard Commandant Instruction manual, COMDTINST M5100.47D Coast Guard Safety and Environmental Health Manual Change 1 February 2022, includes extensive changes to Chapters 3, 20, 21, and 28 from the previous version. This Manual sets forth the key elements of the Coast Guard’s Safety and Environmental Health (SEH) Program, assigning responsibilities for the implementation of those program elements and specifying the SEH standards that are to be applied within the Coast Guard. Chapters within this Manual contain policy and responsibilities, applicable across all missions and mission support operations, including the operational community (aviation, afloat, and shore-based units). All Coast Guard Area Commanders, Sector/Group Commanders, Commanding Officers, Officers-in-Charge, Deputy/Assistant Commandants, and Chiefs of Headquarters staff elements must comply with provisions of this Manual.