We are moving into a new paradigm of hyper-accelerated decision making, where artificial intelligence and machine learning facilitate automated action at a pace and scale that human minds alone cannot keep up. We need to respond to this challenge by combining artificial and human intellect to build a cognitive advantage, which is the demonstrable superiority gained through comprehending and acting to shape a competitive environment at such a pace that an adversary’s ability to comprehend and act is compromised. In the longer term, cognitive advantage provides the means to cultivate the broader sustainability of the environment on which the organisation depends. This book provides context for this trend, summarises relevant scientific understanding and codifies the distinguishing features of the type of organisation that will succeed and lead in this new competitive landscape – the cognitive enterprise.