This book analyzes the ecology and management of ticks and explores Lyme disease at national parks in the eastern United States. Focusing on the northern deer tick, the author examines habitat distributions and infection rates of ticks and Lyme-causing bacteria. Further exploration into the role of vertebrate hosts and tick immigration rates on Lyme disease prevalence sheds light on the intricate dynamics of tick-borne infections. The book employs mathematical models to analyze the spread of Lyme disease through animal populations, considering the influence of host competence and tick immigration. The author also discusses methods to control ticks, including the efficacy and environmental impact of using permethrin-treated cotton balls. With Lyme disease continuing to pose risks, this book provides a timely analysis of tick ecology, Lyme disease transmission, and management strategies, offering valuable insights for those seeking to minimize the risks associated with tick-borne diseases.