VEHICLE APPLICATIONS: Mercedes-Benz (G550 2010-13, GL320 2007-09, GL350 2010-13, GL450 2007-12, GL550 2008-12, ML320 2007-09, ML350 2006-13, ML450 2010-11, ML500 2006-07, ML550 2008-11, ML63 AMG 2007-11, R320 2007-09, R350 2006-13, R500 2006-07, R63 AMG 2007) FILTER CROSS REFERENCES: Mercedes-Benz 1648300218; Premium Guard PC9376; Purolator C16081C EASY INSTALL: This cabin air filter is located behind the glove box and on average will only take 15 minutes to replace the old filter with a new filter. It is important to replace your cabin air filter periodically to help keep the air in your vehicle clean. During extreme weather and heat, the HVAC system has to work harder and a clean cabin air filter is essential in helping your HVAC system run more efficiently. FRAM Fresh Breeze cabin air filters are the only cabin air filters built with Arm & Hammer baking soda combined with carbon embedded in the filter. Cabin air filters have proven to be essential as air quality can be severely affected by wildfire smoke, pollen, dirt, and other irritants. It is important to replace your cabin air filter periodically to help keep the air in your vehicle clean. This cabin air filter will help protect your vehicles heating and air conditioning unit while allowing for the most efficient air flow into the cabin of your vehicle.