Spacers are devices that are used with nebulizers and metered dose inhalers that are comprised of a reservior into which an aerosol medication is dispensed. A spacer uses an open mouthpiece. Spacers are intended to minimize delivery of large aerosolized particles. Spacers are frequently made of plastic, and can be tube shapped. By holding drugs after aerosolization, spacers are intended to minimize delivery of large aerosolized particles, which would otherwise deposit in the mouth. Spacers contact the mouth. The drug they are holding is intended for the lower airways Spacer, Direct Patient Interface