When Doctor Katie Walsh returns to South Boston and resumes old friendships from her younger days, her world is turned upside down by events beyond her control. Searching for answers, her personal beliefs are shaken to the depths of despair and she’s consumed by the ageless quest for retribution. Meanwhile, Mrs. Modica and Jack “The Junk Man” Jenkins battle their own demons. Facing doubt and despair, they, along with Doctor Walsh, hope to resolve their personal dilemmas before all their lives are lost in darkness and regret. Hope & Despair (The Southie Pact Part Two) introduces new characters, hoping to further raise awareness of drug addiction.