Bradley's longtime adversary, Ali al-Haqani has lived to see another day and he's elevated the devastation to a new level with global consequences. Bradley, with the help of his FBI colleagues and Dr. Audrey Howe of the Centers for Disease Control must discover how and why people in the heartland of the U.S. are dying in record numbers. In the midst of the global chaos, a matter hits Bradley too close to home and it may become a distraction.