The New York Times bestselling author of Fat Chance explains the eight pathologies that underlie all chronic disease, documents how processed food has impacted them to ruin our health, economy, and environment over the past 50 years, and proposes an urgent manifesto and strategy to cure both us and the planet. Dr. Robert Lustig, a pediatric neuroendocrinologist who has long been on the cutting edge of medicine and science, challenges our current healthcare paradigm which has gone off the rails under the influence of Big Food, Big Pharma, and Big Government. You can't solve a problem if you don't know what the problem is. One of Lustig's singular gifts as a communicator is his ability to "connect the dots" for the general reader, in order to unpack the scientific data and concepts behind his arguments, as he tells the "real story of food" and "the story of real food." Metabolical weaves the interconnected strands of nutrition, health-disease, medicine, environment, and society into a completely new fabric by proving on a scientific basis a series of iconoclastic revelations, among them- medicine for chronic disease treats symptoms, not the disease itself. You can diagnose your own biochemical profile. Chronic diseases are not "druggable," but they are "foodable".