New Developments in Redox Biology: Fundamental Roles in Health and Disease

$200.00
by Asim K. Duttaroy PhD

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New Developments in Redox Biology: Fundamental Roles in Health and Disease serves as a vital resource for understanding the profound impact of the redox system on human biology. In the book, readers are introduced to the intricate balance of oxidative stress, the delicate mechanisms of antioxidant defense, and their pivotal roles in cellular function. This book meticulously unpacks the connections between redox biology and the progression of health, aging, and disease, offering researchers and enthusiasts alike a window into these complex physiological processes. Aside from illuminating oxidative dynamics, this book delves into emerging trends, therapeutic potential, and the integration of redox principles in developing medical interventions, highlighting its relevance in advancing human health. Explores the fundamental role of redox biology in developmental processes and cellular homeostasis - Investigates the impact of oxidative stress on non-communicable diseases, including cancer, metabolic, and autoimmune disorders - Examines redox regulation in infectious diseases and host-pathogen interactions - Provides detailed insights into redox-related biomarkers and their diagnostic and therapeutic potential - Equips readers with cutting-edge knowledge on redox biology through multi-omics approaches Explores the critical role of redox biology in developmental biology, non-communicable diseases, and infectious diseases New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a comprehensive exploration of the influence of the redox system and the complex relationships between oxidative stress, biological development, health and disease. Divided into three sections, it explores the role of the redox system across developmental biology, non-communicable diseases, and infectious diseases. The first section includes chapters exploring oxygen availability in embryonic development, the influence of stress factors and intra-cellular signalling during embryogenesis, and how stem cells maintain homeostasis under oxidative stress. Section two considers topics such as the origin of cancer stem cells related to hypoxia, redox-related biomarkers in tumorigenesis and metabolic disorders, and the role of oxidation and reduction systems in autoimmune disorders and neurodegeneration. The final section focuses on redox regulation in infectious illness and includes chapters on redox biomarkers in host-pathogen interaction, the role of redox control in zoonotic diseases, and the significance of hypoxia on the ability of microbial pathogens to invade the gut. Antiviral drugs and the use of redox regulation in their mechanism of action is also explored. New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a multidisciplinary approach to the topic, providing valuable insights to those seeking to expand their expertise in redox biology and its implications for human health and disease. In particular, researchers and advanced students working across molecular biology, cell biology, biochemistry, developmental biology and related fields will find this book useful. Dr. Asim K. Duttaroy is a professor at the Faculty of Medicine, University of Oslo, Oslo, Norway. His research programs focus on the roles of food components on growth and development, as well as in the prevention of diseases such as diabetes and cardiovascular disease. He is also investigating the roles of the antiplatelet and antihypertensive properties of fruits and vegetables. His discoveries of antithrombotic factors in tomatoes and kiwifruits are patented internationally, and three companies (Provexis Limited in the United Kingdom, IDIA AS in Norway, and Genimen Pharmacon in India) are working to commercialize these discoveries. He has published over 265 original contributions and reviews, 6 books, and several book chapters and editorials, and he is the Editor-in-Chief of the journal Food & Nutrition Research, as well as a guest editor of several journals such as Nutrients and Frontiers in Physiology. Dr. Atala Bihari Jena has a PhD in Biotechnology and over 7 years of experience in redox biology. He is an MK-Bhan Fellow at the National Center for Cell Science, Savitribai Phule Pune University, India and his main research expertise centres on oxidative stress, antioxidant enzymes, antioxidants, and the cellular redox system in health and disease.

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