After saturation of entire plant, our spray will adhere to the target insect, egg case or larvae. It's active ingredients then cause disruption of respiration and digestion. It also penetrates to dehydrate their entire body. Insects can never become immune to this product because they can't get immune to suffocation or dehydration. Lost Coast Plant Therapy was designed to suffocate and dehydrate on contact. That is why it is important to thoroughly saturate your infested plants. If the product does not contact the insect it can't suffocate or dehydrate it. Lost Coast Plant Therapy was designed to suffocate and dehydrate on contact. That is why it is important to thoroughly saturate your infested plants. If the product does not contact the insect it can't suffocate or dehydrate it. Many insects and diseases are killed on contact with one application. Others, take repeat application to eliminate the problem. Our unique formula does not stress the plant and will not damage flowers, fruits or vegetables as long as it is applied under proper lighting and low heat conditions.