The book, Quality Management System in the Medical Laboratory is a very well researched and written piece of work. It will be highly sought after by all interested in running and offering a quality-driven medical laboratory service. The author has brought his vast knowledge and practical experience in guiding medical laboratories through the achievement of ISO 15189 standard quality journey to bear on the book. The book is divided into well referenced seven chapters, chapter one lays out the critical role of laboratory investigation in healthcare, giving an overview of the statutory framework for laboratory practice in some clinics. Chapter two focuses on the pre-analytical factors that affect the accuracy and quality of laboratory test outcome and results. Chapter three dwells on quality assurance practice in medical laboratories. Chapter four discusses the need to institutionalise quality management system in hospital settings to minimize and prevent medical errors which often lead to unintended harm to patients and clients. Chapter five discussed the intervention of the World Health Organisation (WHO AFRO) in promoting the adoption of quality management system in resource challenged settings for strengthening laboratory practice. This includes the Stepwise Laboratory Improvement Process Towards Accreditation (SLIPTA), which is a framework of auditing based on the ISO 15189 Standards Institute (CLSI), as well as Strengthening Laboratory Management Towards Accreditation (SLMTA) which advocates the use of audit tools to enhance and accomplish quality improvement tasks. Chapter six discusses the interesting case study of the journey of the 445 Nigerian Air Force Hospital (NAFH) Laboratory Ikeja and how it became the first medical laboratory in Nigeria to achieve the 5-Star grading in 2013 by the Africa Society for Laboratory Medicine (ASLM) based on the WHO AFRO SLIPTA Checklist. The author describes in detail the concept, process and transition of the laboratory from its 5-star rating ISO 15189:2012 accreditation in 2016. He shared his personal experience, lessons learned and made elaborate recommendations for laboratories preparing for accreditation. Chapter seven crowns the book by discussing and laying out in exhaustive technical detail the practical steps for Writing Quality Manual, an indispensable activity in achieving the goal of Quality Management System, thereby equipping the reader and all those interested in the pursuit of quality practice in the medical laboratory with all they need for its achievement and sustenance.