5-in-1 Protection: One simple-to-apply, monthly application protects your dog from fleas, ticks*, ear mites, heartworm disease, and sarcoptes mites. Revolution has a 20+ year history working to protect tens of millions of pets. Easy-to-Apply: Revolution doesn't require gloves or separation time. It's quick-drying, pre-measured, and applied topically on the back of your dog's neck. Wash hands after use. Control You Can Count On: Effectively treats and controls infestations of common parasites, including American dog ticks* and ear mites, sarcoptic mange, while breaking the flea life cycle by killing adult fleas and preventing flea eggs from hatching. Year-Round Heartworm Disease Prevention: When given monthly, Revolution prevents the development of adult heartworms. Confidence in Every Application: Approved for dogs 6+ weeks old with no minimum weight. It has been tested safe in over 100 different pure and mixed breeds of healthy dogs, including pregnant & lactating females, breeding males & females, Avermectin-sensitive collies, and, heartworm positive dogs.