The Asia-Pacific region has made considerable progress towards the Millennium Development Goals (MDGs), but the region is still off track on many crucial MDG indicators. This publication considers the challenges the region faces for achieving the Goals and shows that they are still within reach, given sufficient determination and financial resources. It starts by estimating the financial needs of the region for closing the gaps in achievement of the MDG targets and identifies potential sources for those funds. It also shows how Asia and the Pacific can take the lead in developing a more inclusive and development friendly financial system. Finally, the report discusses challenges to including technology and finance- for promoting growth that is inclusive and sustainable to green growth to that will help the region achieve the MDGs.