A humorous mystery starring the world’s most famous detective, and his cat. Sherlock Holmes is suffering from melancholia. Cat Watson, his new detecting companion, has vanished. It has been three long weeks since the detective last laid eyes on the small black cat. Sherlock fears he has come to a bad end, hence the melancholia. There are pressing cases clamouring for the detective’s attention, but finding Cat Watson is the only one that interests him - until his brother Mycroft also disappears under very peculiar circumstances indeed. Dr. John Watson is no help whatsoever. He has proclaimed himself to be a client and is badgering Sherlock to solve The Mystery of the Missing Watch. It should be a simple undertaking, yet it is proving to be a thorn in Sherlock’s side. Or perhaps the thorn is John himself. Sherlock would surely have all three cases wrapped up in a trice, if only a shadowy adversary would stop trying to kill him. And The Mystery of the Single-Minded Assassin is the fourth and deadliest puzzle the detective must solve, if he is to stay alive. Sequel to Volume 1