One of the most important events that took place in Rome during the Great Jubilee year was the International Conference on Science and Faith, "The Human Search for Truth: Science, Philosophy, Theology. The Outlook for the Third Millenium," held at the Vatican in May 2000, as part of the Jubilee for Men and Women from the World of Science (Giubileo degli Scienziati). "Science" is here understood in its broadest sense, thus encompassing the experimental sciences, the human sciences, and the sciences of the spirit ---- philosophy and theology. Organized by the Pontifical Council for Culture, this conference emphasized the search for truth as a distinctive feature of all scientific inquiry by promoting a rediscovery of the sapiential dimension of the sciences: that is, research into nature and humanity must include a deeper awareness of its human dimension and of the human values which undergird it, so that knowledge of the world increases, so too will the ethical values that give life meaning. Saint Joseph's University Press is pleased to make available this collection of the papers presented at this groundbreaking conference that marks a watershed in the renewed effort on the part of the Catholic Church to build bridges between the worlds of scientific research and theological reflection.