The book explores engineering as a profession as well as the leadership role of engineers in shaping modern society . A review of the generalized approach to engineering, which is common to the various engineering disciplines, is presented. It emphasizes the unique nature of engineering, which is based on integration of science & engineering science with design, art & experience. Successful engineering and engineers, as well as efficient education of engineers, need to optimize the balance between these cornerstones. Together they make up the fundamentals required for creativity and innovative approaches in engineering. The book deals with a range of issues encouraging every engineer to exercise a holistic approach , which is based on integration of key elements such as relations and interactions between science & engineering; engineers as decision makers; uncertainties, reliability & failure prevention; responsibility and ethics; engineering and society; education of engineers in the modern era.